5 years after it appeared, things we know and still don’t know about COVID

FILE PHOTO: Employee Philipp Hoffmann, of German biopharmaceutical company CureVac, demonstrates research workflow on a vaccine for the coronavirus (COVID 19) disease at a laboratory in Tuebingen

What do we know about long COVID?

Millions of people remain in limbo with a sometimes disabling, often invisible, legacy of the pandemic called long  COVID.

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It can take several weeks to bounce back after a bout of  COVID-19, but some people develop more persistent problems. The symptoms that last at least three months, sometimes for years, include fatigue, cognitive trouble known as “brain fog,” pain and cardiovascular problems, among others.

Doctors don’t know why only some people get long COVID. It can happen even after a mild case and at any age, although rates have declined since the pandemic’s early years. Studies show vaccination can lower the risk.

It also isn’t clear what causes long COVID, which complicates the search for treatments. One important clue: Increasingly researchers are discovering that remnants of the coronavirus can persist in some patients’ bodies long after their initial  infection, although that can’t explain all cases.

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